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Schoenenberger 1984
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A recent study shows that upregulation of Nrf2 gene expression in a mice experiment led to increased NQO-1 protein content and activity, as well as elevated HO-1 protein content and activity in the brain, while in the liver, HO-1 activity and mRNA levels, NQO-1 activity, and protein content were augmented (92).This study reveals the tissue-specific regulation of Nrf2 signaling and downstream antioxidant enzymes in the mice, highlighting its adaptive response to varying oxygen concentrations
Retrieved September 23, 2021, from Hirayama, S., Terasawa, K., Rabeler, R., Hirayama, T., Inoue, T., Tatsumi, Y., Purpura, M., & Jger, R
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