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Avoid Stimulants Stimulants, such as caffeine, alcohol, or energy drinks, can worsen adrenal fatigue symptoms by: Overwhelming the adrenals through increased release of stress hormones

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Design Origin: Modeled after the natural hGH fragment 176191, but refined for targeted research applications

For general safety guidance, see our peptide safety guide

If retatrutide pushes someone from a resting rate of 92 to 102, that crosses into a range where cardiac workload becomes a genuine concern, especially over months of treatment