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J.et al (2021)

Individual outcomes vary depending on health factors, lifestyle, and treatment adherence

These transcriptional effects of SREBP include (but are not limited to) increased expression of glucokinase (encoded by GCK), liver pyruvate kinase (encoded by PKLR), lipoprotein lipase (encoded by LPL), fatty acid synthase (encoded by FASN), and acetyl-CoA carboxylase 1 (encoded by ACACA), and decreased expression of glucose 6-phosphatase (encoded by the G6PC gene), fructose 1,6-bisphosphatase (encoded by FBP1), and mitochondrial phosphoenolpyruvate carboxykinase (encoded by PCK2)

Corneal stroma demarcation line after standard and high-intensity collagen crosslinking determined with anterior segment optical coherence tomography

If levels are at the low end of normal, supplementation to get the level into the middle or upper end of the normal range may slow development of symptoms. This is somewhat similar to Prof