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PMID: 37591245 Semaglutide ameliorates cognition and glucose metabolism dysfunction in the 3xTg mouse model of Alzheimer's disease via the GLP-1R/SIRT1/GLUT4 pathway

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Real-world data presented at ASCO 2026 suggests GLP-1 receptor agonists may reduce metastatic progression of certain obesity-related cancers lung, breast, colorectal, and liver [7]

4.1 Insulin-like growth factor binding protein-like 1 (IGFBPL-1) IGFBPL-1 shares sequence similarities with IGFBPs, suggesting a potential role in binding IGFs and modulating their activity