The most common adverse effects include nausea, vomiting, diarrhea, constipation, decreased appetite, and abdominal discomfort
LCFAs are prevalent substrates in the myocardium at rest and during prolonged exercise in skeletal muscle (Stubbs and Smith, 1984
Indeed, measurements of noradrenaline (NA)-induced aerobic glycolysis by FRET nanosensors in individual astrocytes demonstrated an increased glucose utilisation, manifested as reduced NA-elevated free cytosolic glucose concentration, whereas the production of lactate by NA was unaltered
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The concentration of leukotriene D(4) (LTD(4)), which is usually not detectable, was highly increased, whereas LTE(4), the major urinary metabolite in humans, was completely absent