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Hydrate, since glutathione is involved in removing waste products through urine

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The inhibition of serine and glycine bidirectional conversion by sertraline prior irradiation reduces the pool of nucleotides, as we previously observed, and concurrent and post-treatment with sertraline might hinder the synthesis of the antioxidant GSH and NADPH production, which exposes cancer cells to the accumulation of endogenous ROS and radiation-induced ROS causing severe oxidative stress [70]

doi: 10.1056/nejmc1602096

FMRI studies tend to demonstrate these patterns with libido-enhancers