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14 Both studies were limited by relatively short follow-up among the included trials, narrow systemic inclusion criteria, limited information on baseline diabetic retinopathy status and, most important, inadequate and non-rigorous methodologies for diabetic retinopathy evaluation

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Notably, a significant portion of albumin in the blood lacks the C-terminal L585 residue, ranging from 3 to 15% in healthy individuals and up to 93% in patients with pancreatitis or other pancreatic disorders 60,61,62