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found that Long COVID patients frequently exhibit a highly elevated Copper-to-Zinc (Cu/Zn) ratio

doi:10.1016/j.fct.2011.11.003

Cappellini, M

Thus, acne can be considered as a visible model disease of exaggerated IIS during puberty aggravated by Western diet, just the opposite of deficient IIS in untreated Laron subjects who do not develop acne [19]

442 The metabolic reprogramming of macrophages to regulate inflammatory conditions provides novel insights into potential treatments for liver regeneration