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However, noticeable effects like improved sleep typically appear within 1-2 weeks, while body composition changes usually become apparent around weeks 6-8

Researchers enrolled 50 adults aged 18 years and older with type 2 diabetes who underwent kidney transplantation at the UAB Comprehensive Transplant Institute from August 2020 to August 2022

If youve had GI upset, hot weather exposure, or youre getting headaches/light-headedness, consider adding electrolytes (or at minimum, some sodium with fluids) and seek medical advice if symptoms are severe or persistent

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Early studies from the late 1990s reported that supplementation at 12 grams per day improved mood and reduced fatigue in patients with major depressive disorder, as evidenced by reductions in Hamilton Depression Rating Scale scores by about 2030% over 48 weeks [5]