Although selective serotonin reuptake inhibitors and cognitive behavioral therapy typically form the first line of treatment for people who have depression, several non-pharmacological adjunct therapies have demonstrated effectiveness in modulating depressive symptoms, including exercise, dietary modification (especially interventions that capitalize on circadian rhythms), meditation, sauna use, and light therapy, among others
1,2 They catalyze the conjugation of glutathione to many organic compounds, so that it can be more easily eliminated from the organism
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Positive aspects
doi: 10.1038/s41421-022-00398-y, Summary Keywords epigenetic regulation, lactate, lactate metabolism, neurological disorders, protein lactylation Citation Chen W, Li R, Zhang J, Lei J, Jiang X and Sun X (2026) From metabolic substrate to epigenetic regulation: roles and mechanisms of lactylation in brain health and disease