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Certain staining techniques cause components of the ribosomes to precipitate into characteristic reticulum (not the same as the endoplasmic reticulum), hence the name reticulocytes
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Epidermal penetration stage: Resistance peak 2.0 Newtons (accompanied by a slight barrier breakthrough sensation) Through the dermal reticular layer: Continuous resistance 1.5 Newtons (similar to the toughness of piercing rubber) Submerging into superficial fat: Resistance drops sharply to 0.2 Newtons (similar to the hollowness of sponge gaps) Touching muscle fascia: Resistance rises back to 1.8 Newtons (a firm and elastic contractile sensation) If during insertion, the resistance value suddenly drops below 0.1 Newtons and is accompanied by obvious pain feedback from the patient, the tip may have slipped into a tiny venous lumen 15 mm under the skin
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