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217:e20201129

Mitochondria are specialized membrane-bound organelles that play key roles in iron metabolism in that they synthesize heme, assemble iron-sulfur proteins, and are involved in the cellular iron regulation

A: While some peptides may be stable at room temperature for short periods, it is generally not recommended for long-term storage due to the risk of degradation and reduced bioactivity

& Gordon, S

351 In the process of ferroptosis, cells are affected by oxidative stress and lipid peroxidation, resulting in the rupture of cell membranes and cell death, which is manifested mainly by the reduction in GPX4, the core enzyme of the antioxidant system (glutathione system), and the high expression of the lipid peroxidation marker 4-HNE