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In this sense, several diseases or conditions or genetic disorders that are predisposing to eryptosis, including deficiency in glucose-6-phosphate dehydrogenase, sickle cell anemia, beta-thalassemia trait, iron insufficiency or deficiency of carriers like GLUT1, AE1 are known to provide a certain degree of defense against a severe malarial course [230, 404]

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This enzyme is specifically designed to dismantle glutathione

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