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Alternatively, the guidelines recommend choosing alternative glucose lowering therapies if cost is a major issue for a patient as these brand-name medications are highly priced [38]

The main importance of carnitine lies in mediating the supply of energy to the skeletal muscles

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Actual muscle building still requires mechanical tension, metabolic stress, and muscle damage from training to trigger the hypertrophy response

Collectively, these findings underscore that cigarette smoking is not only associated with an increased risk of developing PBC but also accelerates disease progression, worsens fibrosis, elevates HCC risk, and contributes to poorer long-term outcomes