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(34) Experimental and clinical studies demonstrate that GLP-1RAs reduce the production of proinflammatory cytokines (e.g., TNF- , IL-6, Interleukin-1 - IL-1) and chemokines (e.g., Monocyte Chemoattractant Protein-1 - MCP-1, CXCL10), while increasing anti-inflammatory cytokines such as Interleukin-10 (IL-10)

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BRET signal was calculated as the ratio of the 535/30 nm emission over the 475/30 nm emission

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