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Male BALB/c-nu nude mice aged 4 weeks and weighing 18 ~ 22 g were purchased from the Experimental Animal Centre of Southern Medical University (Guangzhou, China) and housed in a specific pathogen-free air-conditioned room (25 2 and 65% 5% humidity) with a 12-h light/dark cycle

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We also proposed that if CMS did not finalize changes to 45 CFR 180.50(b)(2)(ii)(C), the dollar amount would be the estimated allowed amount under the current regulations