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Constipation Slowed digestion can lead to bloating and constipation

Use antioxidants, if tolerated, to neutralize reactive intermediates (glutathione, vitamin C, selenium)

So we need therapies for those individuals

Research has shown that GLP-1 agonists can lead to a significant reduction in caloric intake by acting on the brain's appetite centres, particularly the hypothalamus, to promote feelings of fullness and decrease the desire to eat