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Glucagon-like peptide-1 receptor agonist semaglutide reduces atrial fibrillation incidence: A systematic review and meta-analysis

In trials, participants on the highest dose lost an average of 20.9% body weight

Monitoring Protocol Watch for: Persistent vomiting Abdominal pain Visual symptoms Excessive weight loss Weakness / falls / sarcopenia signals This is good practical OPD monitoring and is aligned with real-world use, though exact frequency should be individualized

However, individuals with restricted diets or absorption issues may require additional supplementation, such as Vitamin B12 injections

Blood tests may include full blood count (to exclude anaemia), renal and liver function, thyroid function tests, vitamin B12 and folate levels, and HbA1c to assess glycaemic control