tirzepatide semaglutide effectiveness comparison generates 7% greater weight loss than #semaglutide in a real-world comparative study. 42% tirzepatide pts lost >15% weight, compared to 19% of semaglutide. https://t.co/L9gyHVj0zs Clinical trials of subcutaneous tirzepatide

Several other molecules/companies are seeking licensing approval for obesity, noticeably tirzepatide (Mounjaro by Eli Lilly), a combined GLP-1 and GIP (Glucose-dependent Insulinotropic Polypeptide) agonist, both of which stimulate insulin secretion

showed IGF-1 overexpression increased muscle mass 15-30% and improved strength in aged mice

It declines with age, and lower NAD+ is associated with slower metabolism and the changes we lump together as getting older. NNMT, meanwhile, consumes the raw materials your body uses to make NAD+ and in fat tissue, NNMT is often overexpressed, which can drag NAD+ down right where you least want a sluggish metabolism

If you find yourself needing daily pain relief, discuss underlying causes (tension, dehydration, dose adjustment) with your healthcare provider rather than relying on daily acetaminophen

Cream and gel formulations For most topical peptide applications to eczema skin, cream or gel formulations with minimal inactive ingredients are preferred