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(b) the study was for a very short term -- four weeks -- and a longer term study should be conducted

The instructions are more than clear enough for a first timer

The titration phase typically lasts 48 weeks, moving through 0.25 mg, 0.5 mg, 1.0 mg, 1.7 mg, and finally 2.4 mg

J Invest Surg 28 , 2431, (2015)