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The original online version of this article was revised: the authors found an error list of authors

Exenatide: Synthetic version of exendin-4, a GLP-1 receptor agonist originally isolated from Gila monster (Heloderma suspectum) venom

The worms can live for approximately 68 years and, during their lifetime, produce millions of microfilariae (immature larvae) that circulate in the blood

| Medication | Monthly Cost (2026) | Mechanism | Avg Weight Loss | |-----------|-------------------|-----------|-----------------| | Retatrutide (compounded) | $200650 | Triple agonist (GLP-1/GIP/glucagon) | 24% | | Wegovy (semaglutide) | $1,300+ | GLP-1 only | 15% | | Zepbound (tirzepatide) | $1,059+ | Dual agonist (GLP-1/GIP) | 21% | | Mounjaro (tirzepatide) | $1,023+ | Dual agonist (GLP-1/GIP) | 21% | | Ozempic (semaglutide) | $935+ | GLP-1 only | 12-14% | *Note: Compounded retatrutide prices reflect direct pharmacy costs with valid prescription

Improving the pharmacokinetic properties of biologics by fusion to an anti-HSA shark VNAR domain