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Several types of cancer have their carcinogenesis associated with the silencing of physiologically beneficial genes, such as tumour suppressor genes, through DNA methylation, 89,90 as described earlier in the article for CDO1

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140 Whereas the continuous supply of FeS clusters by NFS1 also prevented the iron-starvation response from being triggered in lung adenocarcinomas, NFS1 suppression was shown to predispose cancer cells to ferroptosis

Br J Clin Pharmacol

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