Understanding how the microbiome is involved in establishing, maintaining, and reversing obesity has been an active area of research 14,15,16 , and has included studies investigating links between the microbiome and obesity-related comorbidities such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) 17,18
Retroviruses , 1996, 12(14), 1373-1381
It has been proposed that PBMCs are sensitive to metabolic alterations in internal tissues, including the liver, and can have the capability to modulate their immunomodulatory properties in response to MASLD/MASH progression [43, 44, 107]
The bottom line is the body needs GLA and most of us in the West are probably not getting enough of it, hence the need to consume a GLA-based supplement such as evening primrose oil
A 29 or 30 gauge needle minimizes discomfort during injection