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Bioconjugated manganese dioxide nanoparticles enhance chemotherapy response by priming tumor-associated macrophages toward M1-like phenotype and attenuating tumor hypoxia

The common standalone ladder starts at 0.25 mg once weekly, escalates every 4 weeks, and reaches a 2.4 mg weekly research-target dose from week 17 onward

Interaction with H1/3 revealed 14 docking solutions at site 5, the DNA-binding domain, where the peptide bound with a minimum energy of 56.49 kcal/mol using the sequence His-Pro-Ser-Tyr-Met-Ala-His-Pro-Ala-Arg-Lys

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