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GLP-1 medications are generally avoided in people with a personal or family history of medullary thyroid carcinoma or MEN2 syndrome, a history of pancreatitis, severe gastroparesis or active gastrointestinal motility disease, pregnancy or plans to become pregnant, or an active eating disorder
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Cagrilintide is a long-acting amylin analogue that reduces appetite and slows gastric emptying, whilst retatrutide is a triple GLP-1, GIP, and glucagon receptor agonist designed to reduce appetite and increase energy expenditure
doi: 10.3390/ijms24119210 [DOI] [PMC free article] [PubMed] [Google Scholar] 63.Chen S, Chen H, Du Q, et al
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