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The FDAs removal of boxed warnings on HRT products last year accelerated a trend that was already well underway

With regard to measure reporting, we estimate a decrease in burden of 267 hours (3,200 HOPDs 50 percent of HOPDs 0.167 hours per HOPD) at a savings of $14,701 (267 hours $55.06/hour) for voluntary reporting for the CY 2025 reporting period and 533 hours annually (0.167 hours 3,200 HOPDs) at a savings of $29,347 (533 hours $55.06/hour) for mandatory reporting beginning with the CY 2026 reporting period

Current medicinal chemistry , 19 1, 126-32

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