and H.R
NSAIDs like ibuprofen (400-600mg every 6-8 hours) combined with ice for 15-20 minutes can reduce inflammation within 48-72 hours when started early
141,142 Recurrent somatic mutation of residues are mainly located at enzymatic active sites that bind to isocitrate, typically at R132 including R132H, R132L, R132S, R132C, and R132G in IDH1, and R140Q or R172K in IDH2
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Hypoglycaemia concerns: Although uncommon with Mounjaro monotherapy, patients using the medication alongside other glucose-lowering agents (particularly insulin or sulphonylureas) may experience nocturnal hypoglycaemia, which can cause night-time awakening, sweating, and disrupted sleep architecture