Our findings are consistent with previous studies showing additional metabolic-cardiovascular-renal benefits of combined GLP-1RA and SGLT2i use in patients with T2D 26 , and suggest a promising role for adding GLP-1RA to SGLT2i therapy in patients with MASLD
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Similar to the thyroid gland, the adrenal gland may also produce insufficient cortisol, with the most common cause being central dysfunction
However, lack of response to RSL3 treatment in non-mutant TPC-1 cells does not strongly support Txnrd1 role in DNA damage induced by RSL3 treatment