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75 Amino acid metabolism Amino acids are the primary substrates for protein biosynthesis, and recent evidence emphasizes the critical role of amino acid availability and metabolism in the regulation of antitumor immunity

Ray SD, Patel D, Wong V, Bagchi D

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On top of that, interactions of biomaterials with erythrocytes, which are the most abundant cells in circulation, are mainly evaluated by in vitro hemolysis testing [465, 466]

The role of glutamine in tumor development and biology is highly influenced by the tumor type, its metabolic requirements, and immune responses, depending on the infiltrated immune cells