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Cellular validation confirms this dual impact of structural remodeling and functional dysregulation: TMAO impairs T-tubule integrity in cardiomyocytes, disrupting calcium transient spatiotemporal synchrony

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[DOI] [PubMed] [Google Scholar] 246.Vlez P.A., Lara-Erazo V., Caballero-Lozada A.F., Botero A., Lozada G., Velsquez A.F., Villegas L.M., Zorrilla-Vaca A

The copper component additionally plays a documented role in superoxide dismutase (SOD) activity, providing a potential antioxidant dimension to joint tissue research