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Variants in GLP1R (the GLP-1 receptor gene that every GLP-1 compound targets), FTO (the fat-mass and obesity-associated gene), MC4R (a melanocortin receptor central to satiety), and TCF7L2 (a transcription factor tied to glucose homeostasis) describe the terrain a clinician prescribes into

With the three together you can actually make a single molecule, like a master key, that opens multiple doors as effectively as [individual] keys, and achieve superior outcomes, Richard DiMarchi, a chemist and chair in biomolecular sciences at Indiana University, told Wired