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Dulaglutide (Trulicity): Given once a week, it improves blood sugar control
When fiber-fermenting bacteria produce butyrate in the colon, the same L cell stimulation occurs
Unlike medication, which has a half-life of several days, natural GLP-1 release happens meal-by-meal
Greenleaf frames the physiology bluntly in the course: the body interprets aggressive caloric restriction as stress or famine and will hold on to weight and break down protein, so adequate protein intake is needed to prevent muscle loss during weight loss
Atomic coordinates and structure factors for the GLP-1RFab7F38 structure has been deposited in the Protein Data Bank with identification code 6LN2
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