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Categories of genetically-determined ancestry in All of Us corresponded directly to categorical ancestry definitions used within gnomAD 11 , the Human Genome Diversity Project 12 , and 1000 Genomes 10 : African/African American, Admixed American/Latino, East Asian, European, Middle Eastern, South Asian, and Other (meaning an individuals predominant ancestry is 0.1 were considered closely related, and to ensure independence of observations, one individual from each related pair was randomly retained

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bacteria that can survive in the absence of certain nutrients are used as a readout for mutagenicity

The availability of multiple matched-batch vials supports consistent experimental conditions across separate study phases, treatment groups, and sampling timepoints