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1991 May 8;57(2):91-4

Taking the injection after a light, protein-rich snack rather than a heavy, greasy dinner may lead to a more comfortable experience

It has been suggested that the FDA-approved dose of 50 mg daily is not sufficient to stimulate human BAT due to low 3-adrenergic receptor expression in human supraclavicular BAT and the effect seen with high doses of mirabegron are instead due to 2-adrenergic receptor agonism [149]