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Amelioration of degenerative phenotypes in park 13 dopaminergic neurons Oxidative stress is one of the major underlying causes of sporadic and familial forms of Parkinsons disease and mainly characterized by an imbalanced GSH/GSSG cycle, enhancing cellular susceptibility to oxidation 37

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Dermatology 15, 514519

Immune effects are restorative, not overstimulating: It rebalances T-cell ratios, upregulates IL-2 in aged tissues, and improves neuroimmune integration, suggesting a targeted recalibration of immune tone rather than indiscriminate boosting. It restores circadian and hormonal rhythms: By stimulating melatonin synthesis, protecting pineal structure, and re-entraining clock genes, Epitalon may counter the widespread circadian drift of aging, with implications far beyond sleep, touching immunity, metabolism, and neuroprotection