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The answer is nuanced and depends on how you approach the combination

doi:10.1038/srep26745 62

6 Low dose may be better tolerated though less well studied for CVD effects

It also means that foundational knowledge about proper handling protocols is more important than ever

In this trial, adults with obesity had average weight loss of 19.5 percent with 10 milligram (mg) doses of tirzepatide, and 20.9 percent average weight loss with 15 mg doses