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According to the FDA-approved prescribing information, gastrointestinal adverse reactions (nausea, vomiting, diarrhea) occur in up to 43% of patients taking Mounjaro and 37% of patients taking Zepbound, with higher rates during dose escalation phases

This underscores the complex bidirectional interplay between peripheral organs and the brain following stroke, mediated through immune and barrier mechanisms

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10.1038/s41569-022-00679-9 64

Co-administration with sildenafil enhanced erectile activity compared to sildenafil alone, offering a potential alternative for patients with inadequate single-therapy responses (6)