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Selenium is a cofactor for enzymes that are present in thyroid cells, such as iodothyronine deiodinase (DIO), which catalyzes the conversion of T4 to T3, thioredoxin reductase (TR), which is involved in the regulation of the redox state, and glutathione peroxidase (GPx), which catalyzes the reduction of H 2 O 2 to H 2 O, using reduced glutathione (GSH) as a cosubstrate

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This fat type is metabolically active and strongly linked to serious health risks including heart disease, type 2 diabetes, cancer, and premature death