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10.1371/journal.pcbi.0030055 PLoS Comput

In contrast to an earlier study that also found such matched contralateral lesions (Werring et al., 2000), this more recent report detected such mirror precursory lesions well before a T2 lesion formed in the index hemisphere, precluding the previous explanation of axonal transection and Wallerian degeneration as a possible contributor to the contralateral mirror abnormality

Because NAC is known to be a very effective free radical scavenger it was used to test this theory

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