One patient, Mistie Mace, lost more than 50 pounds and was able to discontinue diabetes medications through this supported, gradual approach
Animal and laboratory studies have suggested that some of these peptides can influence blood vessel formation which from an injury perspective, can indicate healing fibroblast activity, collagen production, reduce inflammation, and improve the healing response in the things that were most interested in from a sports medicine and surgery perspective: tendons, ligaments, muscles, cartilage, and other tissues, Frank said

Summer and I discuss: What food noise is, and how it goes far beyond hunger or cravings Her personal experience with obesity, weight loss, and taking GLP-1s Overlap between food noise, chronic dieting, and disordered eating patterns Who should (and shouldn't) be on these drugs Risks and benefits of GLP-1 use in different populations The importance of ongoing professional support while using GLP-1 meds Why inappropriate GLP-1 use cases shouldnt overshadow people genuinely benefiting from these medications How weight stigma and judgment can make conversations around GLP-1 use even more difficult Why compassion, individualized care, and ongoing professional support matter I hope this episode helps you better understand GLP-1 medications and the experiences of those who use them
For patients with BMI 35 with comorbidities or BMI 40, bariatric surgery remains the most effective intervention for sustained weight loss, producing mean loss of 2535% of body weight maintained over 510 years
Some users report increased hair shedding during treatment, but current clinical data have not identified hair loss as a confirmed direct side effect of retatrutide