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Abbreviations DPP-4: Dipeptidyl peptidase-4 GIP: Glucose dependent insulinotropic peptide GLP-1: Glucagon-like peptide-1 NEP: Neutral endopeptidase References Wewer Albrechtsen NJ, Kuhre RE, Torang S, Holst JJ (2016) The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs

Retatrutide simultaneously targets GLP-1, GIP, and glucagon receptors, making it distinct from approved agents such as semaglutide (Wegovy) and tirzepatide (Mounjaro)

It damages the DNA of your skin cells, and they start to grow out of control

Retatrutide works via a completely different mechanism to other weight loss drugs such as orlistat and phentermine focusing on hormonal regulation rather than just suppressing appetite or blocking fat absorption

Lets break it down clearly and practically so you can decide based on how your skin works, not just trends