Their mechanism of action involves several complementary pathways: Enhancing glucose-dependent insulin secretion from pancreatic beta cells, which helps lower blood glucose levels when they are elevated Suppressing glucagon release from pancreatic alpha cells, reducing hepatic glucose production Slowing gastric emptying , which moderates the rate at which nutrients enter the bloodstream Promoting satiety through central nervous system effects, leading to reduced appetite and caloric intake These combined effects result in improved glycaemic control in people with type 2 diabetes and significant weight loss in those using higher doses for obesity management
There were no cases of glucose intolerance, insulin resistance, edema (fluid retention), joint pain, carpal tunnel syndrome, or other manifestations of excess growth hormone activity
Be aware of the signs of B12 deficiency, such as fatigue, weakness, and skin changes
It can complement other therapies such as bronchodilators, corticosteroids, and antibiotics, potentially improving treatment outcomes and symptom management
With support, small changes can lead to lasting results