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Results from the phase 2 TROPION-Lung05 trial published in the Journal of Clinical Oncology revealed that among 137 patients given 6 mg/kg of dato-DXd every 21 days for pretreated NSCLC, the confirmed ORR was 35.8% (95% CI, 27.8%-44.4%), including 32.8% of patients experiencing a partial response and 2.9% having a complete response

Environmental modifications can reduce frequency by 30-50%: maintain bedroom temperature between 60-67F, use moisture-wicking fabrics, and avoid alcohol within 3 hours of bedtime

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Gallbladder Removal (Cholecystectomy) Acute biliary pain from gallstones, in the absence of complications, can be treated with pain relievers (Tanaja 2018)

Collectively, these findings advocate for a personalised, clinically guided approach to probiotic supplementation