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Molecular basis for the regulation of angiogenesis by thrombospondin-1 and -2

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Treatment of cells with deacetylase inhibitors, i.e., SAHA and TSA, to inhibit classical HDACs and nicotinamide (NA) to inhibit sirtuins, shows that SnCE1 acetylation increases suggesting acetylation to be enzymatically regulated by human deacetylases (Fig

Sivanand and Vander Heiden, 2020