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While not yet approved, its development represents a major step forward in oral weight management treatments

And I think the big question is to determine whether improvements in disease activity that we might see, whether they're entirely due to weight loss, or are there actually direct anti-inflammatory effects of these medications, which could be really interesting

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As of March 2026, two trials are actively recruiting new participants: the Maintenance trial (NCT06859268, testing dose reduction after initial weight loss) and a new enrollment trial (NCT07232719, 250 participants with obesity or overweight)