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This places GHK-Cu in the category of a supportive adjunct: something you might layer into a topical protocol for scalp health, anti-inflammation, and perhaps a modest boost in local 5AR1 inhibition not a replacement for pharmaceutical inhibitors

NADPH nicotinamide adenine dinucleotide phosphate SAH: S-adenosylhomocysteine SAM: S-adenosylmethionine Sarc: sarcosine Ser: serine THF: tetrahydrofolate References Wu G, Fang Y, Yang S, Lupton JR, Turner ND: Glutathione metabolism and its implications for health

Last reviewed: June 12, 2026 Last updated: June 12, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

In the end, theres no one-size-fits-all when it comes to these medications

[Krimberg & Wittandt Biochem Z 251 231 1932, Strack et al