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In the TRANSCEND-T2D-1 trial (published in The Lancet , June 2026), individuals with type 2 diabetes lost -15.3% at 12 mg over 40 weeks

doi: 10.26355/eurrev_202004_20985 267 FuXSongGNiRLiuHXuZZhangDet al

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Mounjaro (tirzepatide) A newer medication that combines two hormones, GLP-1 and glucose-dependent insulinotropic polypeptide (GIP), Tirzepatide (Mounjaro/Zepbound): Dual GIP/GLP-1 agonist