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Toxicology and Applied Pharmacology

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2.10 Gut microbiota analysis 2.10.1 NGS amplicon sequencing The microbiota in the fecal slurry was analyzed using the NGS technology

10.1002/BDD.1816 36 WangJ.XiangH.LuY.WuT.JiG

Ozempic as an add-on to basal insulin and Ozempic 1 mg vs 2 mg SUSTAIN 5: add-on basal insulin 1,10 In patients with type 2 diabetes on basal insulin metformin Secondary endpoint: mean change in body weight from baseline to Week 30 Mean baseline: 202 lb SUSTAIN FORTE: Ozempic 1 mg vs 2 mg 1,4,8 In patients with type 2 diabetes on metformin sulfonylurea Secondary endpoint: mean change in body weight from baseline to Week 40 Mean baseline: 219 lb Results based on sensitivity analyses of retrieved dropout population