any glp 1 oral GLP-1 receptor agonists are generating a great deal of excitement as a potential inflection point in diabetes and obesity care. Amid the enthusiasm, however, a quieter and clinically important issue is A Pill to Fight Obesity

Headaches and dizziness During the first few weeks, some individuals may experience mild headaches or dizziness

Recommendations for the peri-operative management of patients taking glucagon-like peptide-1 receptor agonists and glucose-dependent insulinotropic peptide [1] : The risk of pulmonary aspiration and mitigation strategies should be discussed with the patient using a shared decision-making approach." "Patients should continue to take glucagon-like peptide-1 receptor agonists throughout the perioperative period." "Patients and clinicians should adhere to recommended fasting guidelines." "Upper gastrointestinal symptoms alone should not be used to determine gastric content." "Regional anaesthesia should be considered as the primary anaesthetic technique, if appropriate." "Point-of-care gastric ultrasound should be considered before induction of anaesthesia to facilitate risk stratification, if appropriate." "Individualised pulmonary aspiration risk assessment should be completed, accounting for drug, patient and procedural factors." "Anaesthesia and airway management should aim to reduce the risk of pulmonary aspiration on induction of anaesthesia, during maintenance and after emergence of anaesthesia

Lancet 359, 20722077

Afamelanotide is authorised in the regulated Scenesse implant for preventing phototoxicity in adults with erythropoietic protoporphyria

The vitamin and dietary supplement chain GNC faced long-standing challenges