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Full-length human growth hormone binds to growth hormone receptors distributed throughout the body, triggering a cascade of effects including stimulation of IGF-1 production in the liver, alterations in glucose and insulin metabolism, protein synthesis in muscle tissue, bone growth and remodeling, organ enlargement with prolonged use, and fluid retention

This behavior closely parallels the one found for humans living in the same area

its the result of chronic inflammation in the plantar fascia, a condition that research and my own clinical experience show rarely resolves without intervention

doi: 10.1111/jcmm.17333

10.1038/s41580-020-0237-9 216 YangW